The treatment of patients diagnosed with schizophrenia exhibiting failing dentition with dental implant placement is understudied. Various factors play a role in treatment success, ranging from bone density to psychiatric symptoms, antipsychotic medication, or compromised oral hygiene. It is therefore imperative for a dental practitioner to recognize these factors and understand the clinical efficacy based on previous literature about placing implants in patients with schizophrenia. We reviewed existing literature on dental implant placement in individuals with schizophrenia, resulting in 3 positive cases of 4 total studies. Nondental implant placement was also reviewed, resulting in 2 positive outcomes of 6. It was concluded that if symptoms can be managed, as exhibited in the 2 positive dental implant case studies, individuals with schizophrenia can be good candidates for dental implantation.